Comparison of the frequency of metabolic syndrome among diabetic and non-diabetic outpatients of a tertiary care public sector hospital in Karachi

ABSTRACT

To compare the frequency of Metabolic Syndrome among diabetic and non-diabetic out-patients of a tertiary care hospital with increased waist circumference. This cross-sectional study was conducted in Medical unit-II of Abbasi Shaheed Hospital, Karachi from September 2008 to January 2009. A total of 100 patients i.e. 50 diabetics and 50 nondiabetics were selected by non-probability, purposive sampling technique. After taking the informed consent, patients of age 30-50 years with waist circumference >102 cm in males and >88 cm in females non-diabetic and diabetic for three years were inducted in the study from out-patient department, while patients having ischaemic heart diseases, nephrotic syndrome and gestational diabetes were excluded. Blood sample was taken for lipid profile and blood glucose after 12 hours of fasting. Waist circumference in straight standing position was measured. Relevant information including age, sex, waist circumference, fasting blood glucose, lipid levels and diagnosis of Metabolic Syndrome were recorded on proforma by a physician and analyzed through SPSS-15. Among diabetics, 62% were males and 38% were females while in non-diabetics, 58% were males and 42% were females. Hundred percent diabetic patients had dyslipidaemia compared to 88% non-diabetics. Among diabetics, 88% were hypertensive while 34% non-diabetics were hypertensive. Sixty percent of diabetics and 28% of non-diabetics had metabolic syndrome [p = 0.001]. There was a significantly high proportion of Metabolic Syndrome with increased waist circumference in diabetic patients