Class I MHC antigens in schistosomal bladder cancer

ABSTRACT

Twenty unrelated non-smoking males with S.haematobium infection were examined. Ten of these patients had biopsy-proven squamous cell carcinoma of the bladder. Ten healthy controls matched for ethnic origin were also included for comparison. Study groups and controls were all typed for HLA-A, -B and -C using the microdroplet lymphocyte cytotoxicity tet. The study showed no higher frequency between any class I MHC antigen in unrelated cases whether with schistosomal cystitis or with schistosomal bladder cancer