Bcl-2 as a marker of apoptosis in type 2 diabetes mellitus with vascular complications

ABSTRACT

Background: vascular complications are the major cause of morbidity and mortality in diabetic patients. Because apoptosis plays a critical role in normal vasculz development and atherosclerosis, we assessed the level of Bcl-2 which is a major anti-apoptotic factor in diabetic patients with and without vascular complications to assess the changes of apoptosis which may occur in diabetic patients