Medical Principles and Practice. 2015; 24 (3): 291-293
en Inglés
| IMEMR
| ID: emr-171530
ABSTRACT
To report a case of teratogenic effect of imatinib mesylate [IM] in a newborn, whose mother was suffering from chronic myelogenous leukemia and was treated with IM for 4 years, including during her pregnancy. Case Presentation and Intervention The newborn was diagnosed with microtia of the right ear, preauricular tag on the left side, absence of right depressor angular oris muscle, and imperforate anus. Infantogram showed dextrocardia, hemivertebrae in the thoracic region and cervical spina bifida occulta. The newborn was operated on for the imperforate anus and was discharged in good condition. This case revealed that IM is not safe for the fetus and leads to teratogenicity. Hence, we recommend that pregnant women should not be treated with IM
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Anomalías Congénitas
/
Anomalías Inducidas por Medicamentos
/
Recién Nacido
/
Embarazo
/
Leucemia Mielógena Crónica BCR-ABL Positiva
Tipo de estudio:
Informe de Casos
Límite:
Humanos
/
Masculino
/
Recién Nacido
Idioma:
Inglés
Revista:
Med. Princ. Pract.
Año:
2015
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