Modulatory effects of Ixora coccinea L. Flower on Cisplatin Toxicity in tumour-bearing mice

ABSTRACT

The active fraction from Ixora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour-bearing mice, treated with cisplatin. It also significantly increased the life span of tumour-bearing mice, treated with cisplatin. Blood urea nitrogen levels of tumour-bearing mice treated with cisplatin were decreased marginally by combination therapy with I. coccinea active fraction