Role of serum zinc and copper in health and disease

ABSTRACT

The study included 637 controls [healthy individuals, malesfemales, 335302] and 1403 patients [malesfemales, 699704] of various diseases. Serum levels of Zinc and Copper were estimated on atomic absorption spectrophotometer [GBC-902] and were compared to their controls. The present study is done by compiling the data of all these studies to evaluate the role of serum Zinc and Copper in health and disease. It was observed that the mean serum zinc level was significantly decreased in pregnancy, acne vulgaris, bum, oral sub mucous fibrosis and malignancy. The mean serum zinc was increased in epilepsy, vitiligo, urolithiasis, primary hypertension and non malignant prostatic disorders. Mean serum copper was significantly increased in pregnancy, thoracic surgery, ischemic heart disease, primary hypertension, oral sub mucous fibrosis and malignancy and it was decreased in epilepsy, burn and prostatic disorders