Effect of in vitro maturation technique and alpha lipoic acid supplementation on Oocyte Maturation Rate: focus on oxidative status of Oocytes

ABSTRACT

Background: Therapeutic potential of in vitro maturation [IVM] in infertility is growing with great promise. Although significant progress is obtained in recent years, existing IVM protocols are far from favorable results. The first aim of this study was to investi-gate whether two step IVM manner change reactive oxygen species [ROS] and total antioxidant capacity [TAC] levels. The second aim was to find the effect of alpha lipoic acid [ALA] supplementation on oocyte maturation rate and on ROS/TAC levels during IVM