[Evaluation of the association between interleukin28B gene polymorphisms and chronic hepatitis C virus infection]

ABSTRACT

Background: It has been shown by recent studies that there is a significant association between genetic polymorphisms near the regulatory of IL28B gene and response to treatment in viral diseases such as hepatitis C. However, genetic factors involving in infection progression to chronic diseases have not been determined yet. In this study, the association of these IL28B polymorphisms with susceptibility to chronic hepatitis C virus infection has been analyzed