role of vascular endothelial growth factor -634 G/C and its soluble receptor on chronic liver disease and hepatocellular carcinoma

ABSTRACT

Background and study aims: the single nucleotide polymorphism [SNP] of the vascular endothelial growth factor [VEGF] gene -634 G/C [rs2010963] influences the progression of hepatocellular carcinoma [HCC]. There have been no studies on the role of VEGF SNP -634 G/C in chronic liver disease [CLD]. The aim of the present study was to analyse the correlation between VEGF SNP -634 and the clinical severity of CLD and HCC