Effect of parathyroidectomy on patients with tertiary hyperparathyroidism [retrospective study]

ABSTRACT

The aim of this work was to study the effect of parathyroidectomy on patients with tertiary hyperparathyroidism. A total number of 10 patients with tertiary hyperparathyroidism manifestations underwent parathyroidctomy, where the patients with adenoma of parathyroid gland underwent excision of adenoma or multiple adenoma, and patients with hyperplasia of parathyroid gland underwent total parathyroidectomy and implantation of a part of one parathyroid gland into the sternomastoid muscle. There were significant changes in clinical and labortatory values between pre- and post-operative measures in both types of patients [adenoma and hyperplasia] where there were significant decrease in serum cacium, serum alkaline phosphatase and parathyroid hormone [P.T.H] and great changes in preoperative manifestations. From this study we can concluded that the optimal treatment of tertiay hyperparathyroidism is surgical excision of edenoma or adenomas, or total parathyroidectomy and transplantation of a part of one gland into the sternomastoid muscle in case of hyperplasia of parathyroid gland