In silico screening and evaluation of the anticonvulsant activity of docosahexaenoic acid-like molecules in experimental models of seizures
IBJ-Iranian Biomedical Journal. 2017; 21 (1): 32-39
en Inglés
| IMEMR
| ID: emr-185665
ABSTRACT
Background:
Resistance to antiepileptic drugs and the intolerability in 20-30% of the patients raises demand for developing new drugs with improved efficacy and safety. Acceptable anticonvulsant activity, good tolerability, and inexpensiveness of docosahexaenoic acid [DHA] make it as a good candidate for designing and development of the new anticonvulsant medications
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Pentilenotetrazol
/
Convulsiones
/
Electrochoque
/
Epilepsia
/
Modelos Biológicos
/
Anticonvulsivantes
Tipo de estudio:
Estudio de tamizaje
Límite:
Animales
Idioma:
Inglés
Revista:
Iran. Biomed. J.
Año:
2017
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