Cell Journal [Yakhteh]. 2017; 18 (4): 532-539
en Inglés
| IMEMR
| ID: emr-185778
ABSTRACT
Objective:
CRISPR/Cas9 technology provides a powerful tool for targeted modification of genomes. In this system, a donor DNA harboring two flanking homology arms is mostly used for targeted insertion of long exogenous DNA. Here, we introduced an alternative design for the donor DNA by incorporation of a single short homology arm into a circular plasmid
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Ingeniería Genética
/
Marcación de Gen
/
Células Madre Embrionarias
/
Técnicas de Sustitución del Gen
/
Recombinación Homóloga
/
Ratones
Idioma:
Inglés
Revista:
Cell J. [Yakhteh]
Año:
2017
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