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Effects of low frequency stimulation on spontaneous inhibitory and excitatory post-synaptic currents in hippocampal CA1 pyramidal cells of kindled rats
Cell Journal [Yakhteh]. 2017; 18 (4): 547-555
en Inglés | IMEMR | ID: emr-185780
ABSTRACT

Objective:

Low-frequency stimulation [LFS] exerts suppressive effects in kindled animals. It is believed that overstimulated glutamatergic and decreased GABAergic transmission have long been associated with seizure activity. In this study, we investigated the effect of electrical LFS on different parameters of spontaneous excitatory and inhibitory post-synaptic currents [sEPSCs and sIPSCs] in hippocampal CA1 pyramidal cells in kindled animals
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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Convulsiones / Ratas Wistar / Células Piramidales / Potenciales Postsinápticos Excitadores / Potenciales Postsinápticos Inhibidores / Región CA1 Hipocampal Límite: Animales Idioma: Inglés Revista: Cell J. [Yakhteh] Año: 2017

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Índice: IMEMR (Mediterraneo Oriental) Asunto principal: Convulsiones / Ratas Wistar / Células Piramidales / Potenciales Postsinápticos Excitadores / Potenciales Postsinápticos Inhibidores / Región CA1 Hipocampal Límite: Animales Idioma: Inglés Revista: Cell J. [Yakhteh] Año: 2017