Oxidative stress biomarkers in exhaled breath of workers exposed to crystalline silica dust by SPME-GC-MS

ABSTRACT

Background: Silicosis is considered an oxidative stress related disease that can lead to the development of lung cancer. In this study, our purpose was to analysis of volatile organic compounds [VOCs] in the exhaled breath of workers exposed to silica containing dust and compare peak area of these compounds with silicosis patients and healthy volunteers [smokers and nonsmokers] groups