Protein tyrosine phosphatase nonreceptor type 22, [PTPN22] gene polymorphism in pulmonary tuberculosis in the Indian population

ABSTRACT

A variant of the protein tyrosine phosphatase nonreceptor type 22 [PTPN22] gene is known to be associated with susceptibility to autoimmune diseases and bacterial infections as it acts as an important regulator of T-cell activation. The objective of this study was to evaluate whether PTPN22-C1858T polymorphism is associated with the resistance to pulmonary tuberculosis [PTB]