Frequency of FLT3 ITD and FLT3 TKD mutations in multiple myeloma patients [a case control study]
IJML-International Journal of Medical Laboratory. 2015; 2 (1): 34-40
en Inglés
| IMEMR
| ID: emr-186343
ABSTRACT
Background and Aims:
multiple myeloma is a malignant proliferation of plasma cells derived from a single clone. The tumor, its products and the host response lead to organ damages. Some factors that are responsible in its pathogenesis are recognized. As FMS like Tyrosine Kinase 3 receptor [FLT3] mutation has been proved as a determining factor in leukemic patients; the goal of this study was to find association of FLT3 internal tandem duplication [ITD] and FLT3 tyrosine kinase domain [TKD] mutations with multiple myeloma
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Índice:
IMEMR (Mediterraneo Oriental)
Idioma:
Inglés
Revista:
Int. J. Med. Lab.
Año:
2015
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