Analysis of transforming growth factor- beta 1 expression in resorptive lacunae following orthodontic tooth movement in an animal model

ABSTRACT

Objective: Root resorption is a complication of orthodontic treatment and till date, there is a dearth of information regarding this issue. The aim of this study was to determine whether the expression of transforming growth factor-beta 1 [TGF-beta 1, an inflammatory cytokine] is related to orthodontic force. Moreover, if associated, the expression level may be helpful in differential diagnosis, control and ultimate treatment of the disease