Serum Antibodies against Helicobacter pylori Neutrophil Activating Protein in Carriers of IL-4 C-590T Genetic Polymorphism Amplify the Risk of Gastritis and Gastric Cancer
IBJ-Iranian Biomedical Journal. 2017; 21 (5): 321-329
en Inglés
| IMEMR
| ID: emr-188489
ABSTRACT
Background:
Gastric cancer arises, mainly, on an inflammatory background. Helicobocter pylori neutrophil activating [HP-NAP] protein functions as a potent pro-inflammatory mediator. Similarly, IL-4 plays a critical role in the inflammation pathway, the levels of which are altered by C to T transition at position -590 in its promoter region. Here, we have aimed to assess the risk of gastritis and gastric cancer in the co-presence of these two inflammation modulating mediators
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Polimorfismo Genético
/
Estudios Prospectivos
/
Helicobacter pylori
/
Interleucina-4
/
Activación Neutrófila
/
Gastritis
/
Irán
Límite:
Adulto
/
Anciano
/
Femenino
/
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Iran. Biomed. J.
Año:
2017
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