Role of MRI in the diagnosis of different bone marrow lesions in pediatric patients with hematological malignancies

ABSTRACT

Background: hematological malignancies are one of the major causes of childhood morbidity; leukemia is the most common of pediatric cancers whereas lymphoma is the third most common childhood malignancy, NHL accounts for approximately 7% of cancers in children younger than 20 years. In patients with hematological malignancies the diagnosis of bone marrow involvement is important to determine prognosis and treatment protocols. MR imaging is the most sensitive imaging modality in the diagnosis of bone marrow infiltration and provides excellent details and additional accurate information about the extent of bone marrow involvement