retrospective analysis of epidemiology prognostic factor and response of treatment of malignant pleural mesothelioma

ABSTRACT

Background: malignant pleural mesothelioma [MPM] represents a common malignant disease. It is an aggressive tumor arising from the mesothelial cells lining the pleura. There is an extremely poor prognosis and a vast majority of MPM patients are diagnosed in an advanced stage. Rapid progression of the disease, no effective therapeutic approach and resistance to chemotherapy and radiotherapy resulted in a median survival time of less than 12 months