Effects of infra red laser on the synovium of mice an experimental study

ABSTRACT

The knee joint of 15 mice were exposed to daily doses of infra-red laser. Five animals were killed after 10, 20 and 30 days of application with an equal number of age matched controls. Histological examination was carried out on paraffin sections stained with Hx, and E. The number of villar profiles of the synovial membrane in the joint were calculated. The volume and surface densities of the synovial membrane in the joint were calculated using stereological techniques. The vascularization of the synovial membrane was also examined. It was found that laser had an enhancing effect on the number of villar profiles, volume and surface densities of the synovial membrane all over the ages. Also, it had an enhancing effect on the vascularization of the synovial membrane all over the ages. The growth pattern of the synovial membrane was preserved. It was concluded that laser application, in therapeutic doses, did not disturb the structural architecture of the synovial membrane and has an enhancing effect on the growth pattern of the synovial membrane