Determination of specificity and pattern of antinuclear antibodies [ANA] in systemic rheumatic disease patients positive for ANA testing

ABSTRACT

Objective: To determine probability of finding antinuclear antibodies [ANA] and anti extractable nuclear antigens [ENA] positive samples and associating ANA patterns with anti-ENA reactivities among a consecutive cohort of samples of systemic rheumatic disease patients referred for ANA testing. Study Design: Prospective cohort study. Place and Duration of Study Immunology Department, Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from January to June 2016