Multiple sclerosis gene therapy using recombinant viral vectors: overexpression of IL-4, IL-10 and leukemia inhibitory factor in wharton's jelly stem cells in the EAE mice model

ABSTRACT

Objective: Immunotherapy and gene therapy play important roles in modern medicine. The aim of this study is to evaluate the overexpression of interleukin-4 [IL-4], IL-10 and leukemia inhibitory factor [LIF] in Wharton's jelly stem cells [WJSCs] in the experimental autoimmune encephalomyelitis [EAE] mice model