Umbilical cord blood platelet lysate as serum substitute in expansion of human mesenchymal stem cells

ABSTRACT

Objective: The diverse clinical applications for human mesenchymal stem cells [hM- SCs] in cellular therapy and regenerative medicine warrant increased focus on developing adequate culture supplements devoid of animal-derived products. In the present study, we have investigated the feasibility of umbilical cord blood-platelet lysate [UCB-PL] as a standard substitute for fetal bovine serum [FBS] and human peripheral blood-PL [PB-PL]