Effect Nigella sativa [black seed] on liver enzymes in ischemia reperfusion injury

ABSTRACT

Background: Hepatic ischemia-reperfusion [I/R] injury may occur in a variety of clinical settings and this remains a significant problem. Oxygen free radicals, produced on reperfusion have been shown to play a major role in hepatic I/R injury. Various therapeutic effects have been described for Nigella sativa. Additionally, it has been presented that Nigella sativa [orientalis] oil has protective effect against ischemia reperfusion injury to various organs. Therefore, it seems possible that the administration of Nigella sativa [orientalis] oil might protect the liver against the ischemia reperfusion injury