Clinical and radiographic comparison between enamel matrix derivative [emdogain] and autologous platelet gel in management of furcation defects in patients with chronic periodontitis

ABSTRACT

This study was carried out to evaluate and compare clinically and radiographically the efficacy of enamel matrix derivative [EMD] and autologous platelet gel [APG] in management of furcation defects in patients with chronic periodontitis. A total of 14 defects were chosen from 10 patients for this study. All patients were subjected to thorough clinical examination in selected sited including plaque index, gingival index, probing depth and probing attachment level. All these clinical parameters were taken prior to surgery and at 3 and 6 months post-surgically. The furcation defects were divided into two groups, the first group was treated with APG, while the second group was treated with EMD. Chemical root biomodification was performed in both groups using EDTA. The selected sites were subjected to densitometric evaluation before and at 3 and 6 months post-surgery. The results of the present study showed that both treatment modalities resulted in a significant reduction in probing depth and attachment loss throughout the follow up period, however, no significant difference between both groups was observed. A more favorable clinical outcome was noticed in furcation defects treated with APG as evidenced by the greater percentage of change in this group. An improvement in mineral content was detected in both treated groups. On comparing both groups, no significant difference in optical densities was observed at various periods of follow up, however, the percentage of change was in favor of group I treated with platelet gel