Assessment of the proliferative marker Ki-67 and P53 protein expression in HBV- and HCV-related hepatocellular carcinoma cases in Egypt
Egyptian Journal of Medical Microbiology. 2007; 16 (2): 415-421
en Inglés
| IMEMR
| ID: emr-197665
ABSTRACT
Background:
Chronic HBV and HCV infections are the major risk factors for the development of HCC through a multistep pathway that involves viral and non-viral dependent pathophysiological steps. Hepatic expression of the nuclear proliferative marker ki-67 and the p53 oncoprotein were found to be associated with poor outcome. So, the present study was done to evaluate the changes in expression of Ki-67 and p53 oncoprotein, and to determine p53 gene mutation in HBV/HCV-related HCC Egyptian patients
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Índice:
IMEMR (Mediterraneo Oriental)
Idioma:
Inglés
Revista:
Egypt. J. Med. Microbiol.
Año:
2007
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