Osteosarcoma: review and diversity of cases

ABSTRACT

Osteosarcoma is the most common primary malignant tumour of bone in adolescents and young adults. It accounts for approximately 15% of all primary bone tumors confirmed at biopsy. There are numerous types of primary osteosarcoma, including are intramedullary osteosarcoma, juxtacortical [surface] osteosarcoma, and extra skeletal osteosarcoma. Osteosarcoma may also occur as a secondary lesion in association with underlying benign conditions. The identification of neoplastic osteoid matrix formation and aggressive characteristics are necessary for histological diagnosis of osteosarcoma. In all bone tumors, differential diagnosis is best assessed with radiographs, whereas staging is performed with computed tomography or magnetic resonance imaging. Beside literature review, we are going to discuss 26 cases of primary osteosarcomas of bone [majority are of conventional type] and 03 cases of extra- skeletal ostcosarcomas