[Evaluation of toxicity chemical substances [extract oihyndropyridine derivatives, saff flower and peganum harmala] By saccharomyces cerevisiae]

ABSTRACT

Background: the toxicity of many chemical substances has been studied by many of living organisms used as biological indicators. Higher organisms[laboratory animals] are generally used but the response time may be lengthy. Never the less by exploiting uni cellular organisms, in particulary yeast, it is possible to reduce testing time considerably. In this study, the budding yeast, saccharomyces cerevisiae asimple non-pathogenic eukaryotic organisms, which is easy to cultivate, has been used as experimental model for assaying acute toxicity of chemical substances