Detection of asymptomatic celiac disease in two siblings from a mother with non-celiac gluten sensitivity
Gastroenterology and Hepatology from Bed to Bench. 2018; 11 (3): 269-272
en Inglés
| IMEMR
| ID: emr-199671
ABSTRACT
Non-celiac gluten sensitivity and celiac disease are known to be two distinct clinical entities, however, non-celiac gluten sensitivity has been detected in a proportion of first-degree relatives of celiac patients. Herein for the first time we describe the occurrence of asymptomatic celiac disease in two siblings, a girl and a boy, whose mother suffered from a proven non-celiac gluten sensitivity. Both the 12-year old girl and 9-year old boy were positive for anti-endomysial and anti-tissue transglutaminase antibodies of IgA class at a very high and low titer, respectively. Duodenal biopsy confirmed the diagnosis of active celiac disease [severe villous flattening] in the girl, whereas her brother had Marsh 1 lesion consistent with a potential celiac disease. This case report indicates that antibody screening for celiac disease can be recommended in any symptomatic or asymptomatic first-degree relatives of patients with nonceliac gluten sensitivity
Buscar en Google
Índice:
IMEMR (Mediterraneo Oriental)
Idioma:
Inglés
Revista:
Gastroenterol. Hepatol. Bed Bench
Año:
2018
Similares
MEDLINE
...
LILACS
LIS