[Evaluation of Factors related death prognosis in hospitalized Tuberculosis patients]

Backgroud: tuberculosis is one of the oldest Known diseases with high annual rates of mortality and morbidity around the globe. A better understanding of factors relating to death prognosis in tuberculosis Patients enhances treatment strategies. this study was conducted for the mentioned purpose

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Materials and Methods: in this case-control study, all cases and controls where matched by age and sex and selected from patients with a definit or suspected diagnosis of tuberculosis hospitalized in the Massih Daneshvari Hospital, during the year 2002. Data were analyzed using non parametric Measures for qualitative variables, X[2][for qualitative variables [CI,OR], and logestic Regression using wald method

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Results: 33 cases were enrolled call passed away; 11 [33%] were female and the rest were male [53þ +/- 16/5]. Half of the deaths occurred in the first six days of hospitalization. 50% of the cases were smokers. 3 [9%] were HIV Positive. In the control group [all alive], Significant differences were found with regard to smoking [P=0.003], PMN count [P=0.001]

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Conclusions: this study suggested that smoking is an important risk factor for mortality in tuberculosis. Smoker TB Patients died 5.6 frequently than non-Smoker. Lymphocytopenic patients had poor prognosis in comparison with normal Lymphocyte counts