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distinct role of small heat shock protein 20 on hcv ns3 expression in hek-293t cell line
AJMB-Avicenna Journal of Medical Biotechnology. 2018; 10 (3): 152-157
en Inglés | IMEMR | ID: emr-202057
ABSTRACT

Background:

Hepatitis C [HCV] is known as a serious blood-borne disease that infects millions of people globally. NS3 is a conserved non-structural sequence of hepatitis C virus which has a major role in activating specific CTL responses. As known, there is no effective vaccine against HCV infection, thus it is required to design a specific regimen of vaccination. Recently, the strong immunological properties of Heat shock proteins [Hsps] led to their use as immunomodulators and an antigen carrier for subunit vaccine candidates. In the current study, the role of Hsp20 was evaluated as a HCV NS3 gene carrier in mammalian cell line
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Índice: IMEMR (Mediterraneo Oriental) Idioma: Inglés Revista: Avicenna J. Med. Biotechnol. Año: 2018

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Índice: IMEMR (Mediterraneo Oriental) Idioma: Inglés Revista: Avicenna J. Med. Biotechnol. Año: 2018