Anti-Mucin1 aptamer-conjugated chitosan nanoparticles for targeted co-delivery of docetaxel and IGF-1R siRNA to SKBR3 metastatic breast cancer cells
IBJ-Iranian Biomedical Journal. 2019; 23 (1): 21-33
en Inglés
| IMEMR
| ID: emr-202859
ABSTRACT
Background:
Targeted co-delivery of siRNA and a chemotherapeutic drug is an attractive approach to cancer drug design and treatment. This study was carried out to design an anti-Mucin1 aptamer [Apt]-conjugated chitosan nanoparticle [NP] for targeted co-delivery of insulin-like growth factor receptor 1 [IGF-1R] Silencer siRNA and docetaxel [DTX] to SKBR3 cells
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Índice:
IMEMR (Mediterraneo Oriental)
Idioma:
Inglés
Revista:
Iran. Biomed. J.
Año:
2019
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