Amniotic fluid fibronectin in post mature pregnancies

ABSTRACT

Firbronectin is a glycoprotein which is involved in coagulation, platelet function, tissue repair, and the integrity of vascular endothelial basement membrane. Amniotic fluid is known to contain a heavily glycosylated variety of firbronectin. We have found a significant reduction in amniotic fluid firbronectin in postmature pregnancies associated with placental insufficiency. A further association was also found between low levels of amniotic fluid firbronectin and increased fetal and neonatal complications