Collagen type III in normal and prematurely ruptured amniotic membranes

ABSTRACT

This work is an attempt to find a relation between type, III collagen fibres in amniotic membranes and PROM [premature rupture of membranes]. Twenty patients with PROM and 20 parturient women with intact membranes [as control] were included in the study. Biopsy specimens were taken from the amniotic membranes near the rupture sites and stained with special stains to assess the amount of collagen fibres III. It was found that type III collagen decreased significantly in PROM as compared with cases with intact membranes