Comparative evaluation of T spiralis IFAT antigens for serodiagnosis of trichinosis

ABSTRACT

A comparative study of three IFAT T. spiralis larval antigens [cuticular, frozen and paraffin sections of muscle larvae] is presented. Hyperimmune anti-Trichinella serum was used to evaluate sensitivity while a battery of human sera assembled from patients with other parasitic infections, non-parasitic eosinophilia, malignant diseases as well as from healthy controls were used to evaluate specificity. Results indicate that frozen sections are more stable in the laboratory [for, at least, one year] and in addition to the ease and rapid preparation, possess higher sensitivity and specificity and so, seem to be more reliable and more promising for serodiagnosis of trichinosis