Effect of clofibrate on lipid levels in various tissues of uromastix hardwiskii

ABSTRACT

Effect of clofibrate on the levels of cholesterol, phospholipids and esterified glycerides in heart, liver, adipose tissue and blood of Uromastix hardwickii was studied. 5 mg clofibrate was injected i.p. and above parameters were estimated using ethanol treated animals as controls. Lipid levels in all these tissues were found to be decreased within one hour and continued to decrease up to six hours. However, in most cases after 24 hours an insignificant increase was observed