Chromatographic studies on experimental candida keratitis

ABSTRACT

Chromatographic analysis and soluble protein contents of aqueous humour and crystalline lens were done in induced ocular infection of rabbit's eyes by Candida albicans in both treated and non-treated inflamed eyes as well as their normal controls. The results showed a significant decrease in the soluble protein contents and molecular weights in aqueous humour and crystalline lens of non-treated eyes. The topical treatment showed an important response which made the treated eyes to be slightly affected by the Candida albicans infections. We conclude from this study that early treatment prevents severe ocular complications and column chromatography is a sensitive technique for protein analysis of crystalline lens and aqueous humour