Immunoglobulin classes G,A,M in brain tumours

ABSTRACT

Serum of 37 brain tumour patients was studied for, Total protein, Protein electrophoresis, IgG, IgA, and IgM in an attempt to ascertain humoral immune response. Findings were compared with 20 healthy subjects, matched for age, sex and socioeconomic status. There was significant rise in alpha-ll globulin, while IgG was suppressed in tumour patients. Decrease of IgG was more marked in patients with malignant tumours. Immunoglobulin A was low in children when compared with adults. Immunoglobulin M remained unchanged