Salvation as a new means for separation of e and z forms of aromatic schiff bases

ABSTRACT

Several Schiff bases I-XI were synthesized by reaction of o- aminophenol or o-aminobenzoic acid and variously substituted benzaldehyde. The rate of condensation was affected by the nature and position of substituents in the phenylimine or benzylidene group. The E and Z forms of each prepared compound were separated by solvation. The structure of each form was established by IR, PMR and elemental analysis. The antibacterial activities of the prepared anils differed from one isomer to the other