Cyanoethylation and mannich reactions with 4-aroyl-6-phenylpyridazin-3 [2H] -ones
Egyptian Journal of Chemistry. 1993; 36 (4): 327-336
en Inglés
| IMEMR
| ID: emr-27924
ABSTRACT
As a part of our recent studies on pyridazinyl ketones[1-3], 4-aroyl-6-phenylpyridazin -3[2H]- ones were recently prepared in this laboratory by a new general and convenient method [1]. We would like to report, in this part, some reactions of these aroyl pyridazinones. When 4- aroyl -6-phenylpyridazin-3[2H]-ones [la-c] were allowed to react with acrylonitrile in ethanol containing catalytic amounts of aqueous sodium hydroxide, they underwent a Michael- type addition to the activated double bond yielding 4-aroyl-2[2'-cyanoethyl]-6-phenylpyridazin-3[2H]-ones[2a-c], respectively
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Índice:
IMEMR (Mediterraneo Oriental)
Asunto principal:
Cetonas
Idioma:
Inglés
Revista:
Egypt. J. Chem.
Año:
1993
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