Clinical and metabolic study of diabetic neuropathy

ABSTRACT

The present study included 150 patients with non insulin dependent diabetes mellitus. They were 111 males and 39 females, aged from 31-66 with a mean age of 50 +/- 7.4 years. The duration of diabetes mellitus ranged from 3-25 years with a mean duration of 8.6 +/- 3.9 years. Clinical results showed that 67 cases of the 150 diabetic patients [44.7 percent] had symptomatic peripheral neuropathy. Out of them, 21 [14 percent] cases had subjective symptoms of neuropathy without objective signs and 46 cases [30.7 percent] showed symptoms and signs of diabetic polyneuropathy. Diabetic autonomic neuropathy was detected in 24 [16 percent] patients; all of them had objective neuropathy. Also diabetic cranial neuropathy was present in 2 [1.3 percent] subjects. There were positive correlations between duration of diabetes and severity of hyperglycemia as well as clinical severity; while age had statistically non significant correlation with both