In-vitro interaction of cypermethrin and permethrin with protein, RNA biosynthesis and some biochemical enzymes in rabbit's liver and brain

The values of biochemical parameters, determined in this work under the influence of permethrin and cypermethrin indicated that, permethrin showed significant decrease of liver and brain RNA and protein biosynthesis, while, cypermethrin had a different effect against liver and brain. It increased brain RNA protein biosynthesis, and liver RNA. At the same time cypermethrin decreased liver protein biosynthesis. On the other hand permethrin and cypermethrin decreased the activities of liver and brain alkaline phosphatase [AP] and monoamine oxidase [MAO], while, they enhanced liver and brain glutamic-oxaloacetic transaminase [GOT] and glutamic pyruvic transaminase [GPT] in adult male rabbits