Effect of acute administration of ethyl alcohol on plasma lipids

ABSTRACT

In the present work, the effect of acute intravenous administration of ethanol on plasma lipid profile was studied. Ethanol was injected in the inferior vena cava of albino rats of both sexes in a dose of 0.8 gram/rat over one hour. Two and four hours later, blood samples were obtained, analyzed for triglycerides, cholesterol, phospholipids, high density lipoprotein cholesterol [HDL.C] and low density lipoprotein cholesterol [LDL.C]. It was found that acute ethanol injection resulted in significant rise in triglycerides, insignificant decrease in cholesterol, HDL.C, phospholipids and LDL.C. These results may be of utmost importance as increasing cardiovascular risks in binge drinkers