Argyrophilic nucleolar organizer regions[AgNORs] in benign and malignant epithelial ovarian tumors

Thirty two cases of epithelial ovarian tumors [24 malignant and 8 benign] were studied for AgNORs count/nucleus. There is a significant decrease in AgNORs in grade 2, 2-3 when compared with grade 1 and benign cases. No significant changes present in AgNORs count between the different histological types. The significant changes in AgNORs count are mostly seen with papillary cystadenocarcinoma