Histological and histochemical studies on the effects of experimental hyper and hypothyroidism on the heart of the albino rat

ABSTRACT

In the present study, 15 male albino rats with an average weight 200 g were used. Induced hyperthyroidism was done. Experimental hypothyroidism was done. The resulting histological and histochemical changes were studied. The heart of hyperthyroid animals presented thickening of the epicardium. There was a decrease in the P.A.S. stained material of the cardiac muscle fibers that most probably indicated a decrease in their glycogen content. In hypothyroid animals, the heart revealed thickening of the epicardium and endocardium. They showed an increased P.A.S. stained material that most probably indicated an increase in their glycogen content