Primary intracranial tumors extramural spread to bone marrow: a report of two cases

ABSTRACT

Intracranial tumours metastasise rarely outside the central nervous system. Metastasis to the bone marrow in isolation from systemic metastasis elsewhere is even more uncommon, although more frequent than is generally thought. Our two cases and their favourable response to chemotherapy make us believe that bone marrow trephine aspiration should be part of the follow up protocol so as to initiate early treatment