Serum lipoproteins in acne vulgaris

ABSTRACT

In order to clarify the obscure pathogenesis of acne vulgaris, serum levels of cholesterol, triglycerides, high density lipoprotein-cholesterol [HDL-C], low density lipoprotein-cholesterol [LDL-C] and very low density lipoprotein-cholesterol [VLDL-C] were determined in 40 female acne patients [20 mild cases and 20 severe cases]. This study showed that the mean values of serum cholesterol, triglycerides, HDL-C and VLDL-C in acne patients did not significantly differ from those of the control group. On the other hand, the serum level of LDL-C was significantly higher in patients with severe acne when compared with that of the controls. Also, it was found that the serum levels of cholesterol, triglycerides, HDL-C, LDL-C and VLDL-C and not significantly differ in severe acne patients when compared with those of mild acne patients