Serum IgM and IgG levels in diabetics with nosocomial urinary tract infection

ABSTRACT

This study included 60 patients from Kasr EI-Eini Hospital suffering from nosocomial urinary tract infection [UTI], 30 of them are diabetics and 30 are non diabetics, and also 20 normal controls. Urine counts and cultures are done to isolate the causative organisms and serum IgM and IgG levels are determined [as a parameter of humoral immunity]. Results of this study revealed that E. coli was the predominant isolate in both diabetics [80%] and non diabetics [70%] followed by Klebsiella [20% in both groups] Pseudomonas aeruginosa was isolated only from non diabetic group [10%]. Both groups showed statistically siginificant increased levels of IgG and IgM when compared to the control group. However, no statistically significant difference was found when both diabetic and non diabetic groups are compared