role of the lung in counter-regulatory hormones in adult-onset diabetes

ABSTRACT

Glucagon, cortisol and growth hormone were estimated by a radioimmunoassay technique in both the pulmonary artery serum samples after cardiac catheterization and arterial blood serum in seven adult-onset diabetics and ten controls. Hyperglucagonemia had been detected in the diabetic group. The lung in the diabetic group consumed a lesser amount of glucagon and cortisol than that of controls. These findings may be a factor in the pathogenesis of hormonal changes in diabetes mellitus